Reishi Mushroom Extract

For Deep Sleep, Calm, and Everyday Immune Resilience

Restless nights. A mind that won't switch off. Seasonal allergies that steal the best weeks of spring. If your nervous system never quite gets the memo to relax, Reishi — the most researched medicinal mushroom on earth, used in Traditional Chinese Medicine for over 2,000 years — can help.

Our Reishi mushroom extract was grown, extracted, and formulated to help your nervous and immune system find its way back to calm.

Why Our Reishi Extract

Formulated to support:

• Nervous system calm and deep, restorative sleep
• Relief from seasonal allergy discomfort
• Healthy immune system function
• Liver, kidney, and prostate health, plus already-healthy blood pressure and cholesterol levels

These statements describe how the ingredients are traditionally used and studied to support the body — see full disclaimer below.

Why We're More Potent Than Almost Anyone Else

Most Reishi extracts on the market are diluted, or made from mycelium grown on grain — not real fruiting bodies. Ours isn't.

Our extract ratio is 1g:4mL — every 4mL dose is packed with 1,000mg of dried, ultrasonically extracted mushroom. That's 2 to 5x more mushroom than most competing extracts.

Here's what that means for you: just $1.50 per day for a clinical-strength dose, grown, extracted, and bottled by us, not a contract manufacturer.

About Reishi

The most well-studied medicinal mushroom in use for more than two thousand years via Traditional Chinese Medicine, Reishi is rich in two compound families researchers keep coming back to:

Beta-Glucans — Reishi contains exceptionally high concentrations (~50% by dry weight), extensively studied for how they modulate immune response and support the body's natural anti-inflammatory processes.

Triterpenoids — a rare and potent compound class studied for antiviral, anti-inflammatory, and organ-protective properties, particularly for the liver, kidneys, and prostate.

Most Reishi products never get tested for triterpene content, so there's no way to know if the medicine is actually there. Every batch of ours is third-party lab tested to confirm appreciable triterpene levels — not just listed on the label, but verified.

Read our full deep-dive on Reishi: "Reishi Mushroom Benefits: What the Research Says About the "Mushroom of Immortality."

What's Actually in the Bottle

Our medicinal mushroom extracts are potent, pure, third-party tested, and contain only:

• 100% organic, U.S.-grown mushroom fruit bodies
• Reverse osmosis filtered & remineralized Appalachian Mountain spring water
• USDA Certified Organic cane alcohol

Yes, that's it.

Choose Your Size

Available in 2 fl. oz and 4 fl. oz bottles.

We recommend starting with a half dose (1mL) for the first 1–2 weeks to let your body acclimate, then moving to the full 2mL daily dose.

Subscribe & save 10% — get your next bottle delivered automatically before you run out.

Grown On Our Farm, Not Imported

We grow the Reishi in Defend ourselves, on our own farm, which is Certified Naturally Grown.

No grains, fillers, mycelium, or imported mushrooms ever go into our products.

Independently Tested, Every Batch

We send our extracts to independent third-party labs to confirm they contain clinically relevant doses of the bioactive compounds you're paying for — including triterpenes and beta-glucans.

View every Certificate of Analysis (COA) on our Lab Results / COA page.

Check out our Reishi Extract Certificate of Analysis here.

Our Extraction Process

We extract using a Hielscher Ultrasonic Processor, engineered in Germany — one of the most efficient extraction methods available. Ultrasonic-assisted extraction lets us pull compounds at very low temperatures, so we never degrade heat-sensitive medicinal compounds.

Learn more about our extraction equipment and technology by checking out our blog post, "Ultrasonic Extraction: Why We Do What We Do."

Our Guarantee

Try it for 30 days. If it's not working for you, we'll refund your order — no questions asked.

Frequently Asked Questions

Is Reishi extract safe to take every day? Yes, Reishi is traditionally taken daily as a long-term wellness tonic. We recommend starting with a half dose for 1–2 weeks to acclimate.

How long before I notice effects? Most people notice improved sleep and a calmer stress response within 2–4 weeks of consistent daily use. Reishi works best as a cumulative, daily practice rather than an as-needed remedy.

Does Reishi interact with medications? Reishi may interact with blood thinners (see Safety Information below). If you take prescription medication, talk to your doctor before starting any new supplement.

What does it taste like? Reishi extract has a naturally bitter, earthy taste — a sign of the bioactive triterpenes at work. Most people take it directly under the tongue or mixed into tea or water.

Is your Reishi grown or wild-harvested? We grow Reishi ourselves, on our own farm, which is Certified Naturally Grown — never imported, never grain-grown mycelium.

Safety Information

Reishi mushroom extract may interact with blood-thinning medications, including Warfarin (Coumadin, Jantoven). If you are pregnant, nursing, taking prescription medication, or have a medical condition, consult your physician before use.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.